PXD024869-2

PXD024869 is an original dataset announced via ProteomeXchange.

Title	Nutlin-3a-induced changes in the proteome of parental and RFX7 knock-out U2OS cells
Description	Mass spectrometry-based whole proteome analysis of parental and RFX7 knock-out U2OS cells treated with 10 µM Nutlin-3a or DMSO solvent control. Ten biological replicates were used.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:30:35.240.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Emilio Cirri
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-19 03:47:42	ID requested
1	2023-03-10 16:19:44	announced
⏵ 2	2023-11-14 07:30:36	announced	2023-11-14: Updated project metadata.

Schwab K, Coronel L, Riege K, Sacramento EK, Rahnis N, H, ä, ckes D, Cirri E, Groth M, Hoffmann S, Fischer M, Multi-omics analysis identifies RFX7 targets involved in tumor suppression and neuronal processes. Cell Death Discov, 9(1):80(2023) [pubmed]

submitter keyword: proteomics, RFX7, Nutlin, Tumor

Steve Hoffmann
contact affiliation	Leibniz Institute On Aging/Fritz Lipmann Institute (FLI) Beutenbergstr. 11; D-07745 Jena; Germany
contact email	Steve.Hoffmann@leibniz-fli.de
lab head
Emilio Cirri
contact affiliation	Leibniz Institute on Ageing Fritz Lipmann Institute Jena
contact email	emilio.cirri@fli-leibniz.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD024869

PRIDE project URI

• PRIDE
  1. PXD024869
     1. Label: PRIDE project
     2. Name: Nutlin-3a-induced changes in the proteome of parental and RFX7 knock-out U2OS cells