PXD024764-1

PXD024764 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomics of Hsp90 inhibition in Leishmania mexicana
Description	Using a combination of mass spectrometry-based quantitative proteomics, chemical and metabolic labelling, we provide the first protein-level evidence that the Hsp90 inhibition affects the expression of hundreds of proteins in Leishmania spp. Our study defines the Leishmania parasite’s response to Hsp90 inhibition at its global proteome and provides a rich resource for future studies on Leishmania biology and antileishmanial drug development.
HostingRepository	PRIDE
AnnounceDate	2021-04-23
AnnouncementXML	Submission_2021-04-23_08:49:39.731.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kalesh Karunakaran
SpeciesList	scientific name: Leishmania mexicana; NCBI TaxID: 5665;
ModificationList	iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-16 04:57:47	ID requested
⏵ 1	2021-04-23 08:49:40	announced

Dataset with its publication pending

submitter keyword: Leishmania, quantitative proteomics

Karunakaran Kalesh
contact affiliation	Department of Chemistry, Durham University, Durham, DH1 3LE
contact email	kalesh.karunakaran@durham.ac.uk
lab head
Kalesh Karunakaran
contact affiliation	Durham University
contact email	kalesh.karunakaran@durham.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD024764

PRIDE project URI

• PRIDE
  1. PXD024764
     1. Label: PRIDE project
     2. Name: Quantitative proteomics of Hsp90 inhibition in Leishmania mexicana