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PXD024749-2

PXD024749 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCX-MS of merozoite surface protein-1
DescriptionThe merozoite surface protein-1 (MSP-1) is the most abundant protein on the surface of the erythrocyte-invading Plasmodium merozoite, the causative agent of malaria. MSP-1 is essential for merozoite formation, entry into and escape from erythrocytes, and is a promising vaccine candidate. We solved monomeric and dimeric structures of full-length MSP-1 construct MSP-1D as previously used in a successful phase 1a clinical trial (Blank et al. 2020). CS-MS was used to validate the de novo built atomic model.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:48:16.744.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPatricia Dijkman
SpeciesList scientific name: Escherichia coli; NCBI TaxID: 562; scientific name: Plasmodium falciparum; NCBI TaxID: 5833;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-03-15 09:13:18ID requested
12024-07-03 01:53:56announced
22024-10-22 06:48:17announced2024-10-22: Updated project metadata.
Publication List
10.1126/sciadv.abg0465;
Dijkman PM, Marzluf T, Zhang Y, Chang SS, Helm D, Lanzer M, Bujard H, Kudryashev M, . Sci Adv, 7(23):(2021) [pubmed]
Keyword List
submitter keyword: MSP-1
Contact List
Mikhail Kudryashev
contact affiliationMax Planck Institute of Biophysics, Frankfurt am Main, Germany
contact emailmisha.kudryashev@gmail.com
lab head
Patricia Dijkman
contact affiliationMax Planck Institute of Biophysics
contact emailpatricia.dijkman@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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