PXD024679-1

PXD024679 is an original dataset announced via ProteomeXchange.

Title	An ERK5-KLF2 signalling module regulates early embryonic gene expression dynamics and stem cell rejuvenation
Description	CCE mESCs were transfected with either empty pCAGGS vector or HA-MEK5DD (S311D T315D) construct for 48 hours. 24 hours prior to lysis, mESCs were either treated with 10uM AX15836 or DMSO control, and transfected mESCs selected with puromycin. Conditions were performed in triplicate.
HostingRepository	PRIDE
AnnounceDate	2021-03-18
AnnouncementXML	Submission_2021-03-18_07:55:46.593.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Greg Findlay
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-03-11 06:21:31	ID requested
⏵ 1	2021-03-18 07:55:46	announced

Dataset with its publication pending

submitter keyword: ERK5-KLF2, signalling, embryonic gene expression, stem cell rejuvenation, TMT, LC-MS, mass spectrometry

Greg Findlay
contact affiliation	The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, the University of Dundee, Dundee DD1 5EH, UK
contact email	g.m.findlay@dundee.ac.uk
lab head
Greg Findlay
contact affiliation	MRC-PPU, University of Dundee
contact email	g.m.findlay@dundee.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD024679

PRIDE project URI

• PRIDE
  1. PXD024679
     1. Label: PRIDE project
     2. Name: An ERK5-KLF2 signalling module regulates early embryonic gene expression dynamics and stem cell rejuvenation