PXD024449 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Characterisation of cancer stem cells and the renin-angiotensin system in colon adenocarcinoma |
| Description | LC-MS/MS Proteomics was performed to determine proteomic differences between colon adenocarcinoma (CA) tissues and patient-matched normal colon tissues, CA-derived primary cell lines and NC-derived primary cells, and between LGCA tissues and cell lines and HGCA tissues and cell lines. Biological processes which may link the renin-angiotensin system and CA were investigated, revealing enrichment of various signalling pathways that may play roles in CA onset and progression directly or via the renin-angiotensin system. |
| HostingRepository | PRIDE |
| AnnounceDate | 2022-08-12 |
| AnnouncementXML | Submission_2022-08-12_02:31:13.769.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD024449 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Danyl Mclauchlan |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2021-03-01 10:02:32 | ID requested | |
| ⏵ 1 | 2022-08-12 02:31:14 | announced | |
Publication List
| Munro MJ, Wickremesekera SK, Tan ST, Peng L, Proteomic analysis of low- and high-grade human colon adenocarcinoma tissues and tissue-derived primary cell lines reveals unique biological functions of tumours and new protein biomarker candidates. Clin Proteomics, 19(1):27(2022) [pubmed] |
Keyword List
| submitter keyword: CRC, colon adenocarcinoma, primary cell lines, LC-MS/MS |
Contact List
| Lifeng Peng |
|---|
| contact affiliation | School of Biological Sciences, Victoria University of Wellington |
| contact email | lifeng.peng@vuw.ac.nz |
| lab head | |
| Danyl Mclauchlan |
|---|
| contact affiliation | Centre for Biodiscovery |
| contact email | danyl.mclauchlan@vuw.ac.nz |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD024449 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD024449
- Label: PRIDE project
- Name: Characterisation of cancer stem cells and the renin-angiotensin system in colon adenocarcinoma
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