PXD024412-2

PXD024412 is an original dataset announced via ProteomeXchange.

Title	KRAS Epitope Identification Immunopeptidomics
Description	Utilizing computational epitope prediction and biochemical assays we predicted and identified high-affinity and/or high-stability KRAS peptides to high prevalence HLA class I molecules. Using single HLA class I allele lines and tumor cell lines in conjunction with MS spectrometry, selected mKRAS epitopes were identified as constituents of the HLA class I ligandome.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:22:28.627.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD024412
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Beatriz Carreno
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; deamidated residue
Instrument	Q Exactive HF; Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-28 22:44:52	ID requested
1	2021-05-29 05:09:42	announced
⏵ 2	2024-10-22 05:22:29	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Cancer Immunotherapy,Epitope, T cells, TCR

Beatriz M. Carreno
contact affiliation	Parker Institute for Cancer Immunotherapy, Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, South Pavilion Tower, Building 421, Rm 8-103 3400 Civic Center Blvd. Philadelphia, PA 19104-5157
contact email	bcarreno@upenn.edu
lab head
Beatriz Carreno
contact affiliation	Univeristy of Pennsylvania
contact email	bcarreno@upenn.edu
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD024412
     1. Label: PRIDE project
     2. Name: KRAS Epitope Identification Immunopeptidomics