PXD024351-1

PXD024351 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Morphine-treated Primary Brain Endothelial Cells LC-MS/MS DIA
Description	This project aimed at investigating the impact of morphine exposure on brain endothelial cells via an in vitro monoculture of primary human brain microvascular endothelial cells (HBMECs) and state of the art mass spectrometry-based proteomics, using a data-independent acquisition (DIA) MS-based quantitative approach. HBMECS were exposed to morphine at three different concentrations (1, 10, 100 uM) and for two different time points (24h and 48h) to explore dose- and time-dependent effects.
HostingRepository	PRIDE
AnnounceDate	2022-03-21
AnnouncementXML	Submission_2022-03-21_01:03:41.783.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sandrine Reymond
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-24 03:03:00	ID requested
⏵ 1	2022-03-21 01:03:42	announced
2	2023-11-14 08:51:21	announced	2023-11-14: Updated project metadata.

Publication List

10.1038/S41598-022-08712-0;

10.1038/S41598-022-08712-0;

Keyword List

submitter keyword: Brain, Endothelial, DIA, LC-MS/MS, Morphine

submitter keyword: Brain, Endothelial, DIA, LC-MS/MS, Morphine

Contact List

Jean-Charles Sanchez
contact affiliation	Translational Biomarker Group, Department of Medicine, University of Geneva
contact email	Jean-Charles.Sanchez@unige.ch
lab head
Sandrine Reymond
contact affiliation	University of Geneva
contact email	sandrine.reymond@unige.ch
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/03/PXD024351
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/03/PXD024351

PRIDE project URI

Repository Record List

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