PXD024294-1

PXD024294 is an original dataset announced via ProteomeXchange.

Title	miR-146 modulation in ALS astrocytes
Description	Regarding astrocytes and microglia, we are looking for pathways related with inflammatory activation, phagocytosis and vesicular/exosome trafficking. Regarding motor neurons, we are searching for pathways related with mitochondrial dynamics, Endoplasmic Reticulum stress, cell death, axonal transport, synaptic vesicles transport and oxidative stress. The general aim is to identify putative hits in ALS that relates with miR-146a expression.
HostingRepository	PRIDE
AnnounceDate	2021-04-06
AnnouncementXML	Submission_2021-04-06_00:20:19.640.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Frank Stein
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-22 01:45:10	ID requested
⏵ 1	2021-04-06 00:20:20	announced

Dataset with its publication pending

submitter keyword: ALS

miR-146a

astrcoyte

motor neuron

microglia

Dora Brites
contact affiliation	Neuron Glia Biology in Health and Disease Group, iMed.Ulisboa, Faculty of pharmacy, University of Lisbon, Lisbon, Portugal
contact email	armvaz@ff.ulisboa.pt
lab head
Frank Stein
contact affiliation	EMBL
contact email	frank.stein@embl.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD024294

PRIDE project URI

• PRIDE
  1. PXD024294
     1. Label: PRIDE project
     2. Name: miR-146 modulation in ALS astrocytes