PXD024243-1

PXD024243 is an original dataset announced via ProteomeXchange.

Title	Cellular proteomic changes in the immediate early phase of HIV-1 and 2 transduction
Description	Human immunodeficiency viruses type 1 and 2 (HIV-1 and 2) are known to depend on cellular host machinery for their replication and survival. While most of the studies on cellular proteomic and transcriptomic changes focused on the late-phase of the infection, studies of those changes in the early time-points; especially in the case of HIV-2 infection, are widely lacking. Using 2nd generation HIV-1 and 2 VSV-G pseudotyped lentiviral vectors, we transduced HEK-293T cells, and carried out transcriptomic profiling and proteomic analysis of harvested cells at 2h time point, which is representative of the immediate early-phase events in the infection cycle.
HostingRepository	PRIDE
AnnounceDate	2021-11-03
AnnouncementXML	Submission_2021-11-03_07:53:11.505.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD024243
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Gergő Kalló
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2021-02-18 10:11:48	ID requested
⏵ 1	2021-11-03 07:53:11	announced

Dataset with its publication pending

submitter keyword: HIV-1, HIV-2, cellular proteome change

Jozsef Tozser
contact affiliation	Department of Biochemistry and Molecular Biology, University of Debrecen, Hungary
contact email	tozser@med.unideb.hu
lab head
Gergő Kalló
contact affiliation	University of Debrecen
contact email	kallo.gergo@med.unideb.hu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD024243

PRIDE project URI

• PRIDE
  1. PXD024243
     1. Label: PRIDE project
     2. Name: Cellular proteomic changes in the immediate early phase of HIV-1 and 2 transduction