PXD024233 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Reading ADP-ribosylation signalling using chemical biology and interaction proteomics |
Description | In this project, we describe a global, proteome-wide screening for ADP-ribosylation interactome. Our data reveals novel MAR and PAR readers. We identify both cell type-dependent and independent ADPr interactors. In addition, we quantify apparent binding affinities of large number of ADPr readers. We also identify proteins, whose interaction with ADPr modifications is regulated upon DNA damage induction. |
HostingRepository | PRIDE |
AnnounceDate | 2021-11-02 |
AnnouncementXML | Submission_2021-11-02_04:14:45.165.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Pascal Jansen |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Orbitrap Exploris 480; Orbitrap Fusion; Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-02-18 06:00:25 | ID requested | |
⏵ 1 | 2021-11-02 04:14:45 | announced | |
Publication List
Kliza KW, Liu Q, Roosenboom LWM, Jansen PWTC, Filippov DV, Vermeulen M, Reading ADP-ribosylation signaling using chemical biology and interaction proteomics. Mol Cell, 81(21):4552-4567.e8(2021) [pubmed] |
Keyword List
submitter keyword: ADP-ribosylation, ADPr-binding proteins |
Contact List
Prof. Michiel Vermeulen |
contact affiliation | Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, 6525 GA, The Netherlands |
contact email | Michiel.Vermeulen@science.ru.nl |
lab head | |
Pascal Jansen |
contact affiliation | Radboud University |
contact email | p.jansen@science.ru.nl |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/11/PXD024233 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD024233
- Label: PRIDE project
- Name: Reading ADP-ribosylation signalling using chemical biology and interaction proteomics