PXD024102 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Tengdan Capsule Prevents Hypertensive Kidney Damage in SHR by Inhibiting Periostin-mediated Renal Fibrosis |
Description | In order to reveal the potential molecular mechanism of TDC in renal protection of rats with essential hypertension, TMT-based quantitative proteomics analysis method was used to conduct quantitative analysis of proteins extracted from kidney of SHR of model and TDC treatment groups after 4 weeks of administration. A total of 5688 proteins were identified by one or more unique peptides. |
HostingRepository | PRIDE |
AnnounceDate | 2021-09-10 |
AnnouncementXML | Submission_2021-09-10_00:46:22.247.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xiaoli DU |
SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-02-10 00:06:54 | ID requested | |
⏵ 1 | 2021-09-10 00:46:23 | announced | |
Publication List
Du X, Tao Q, Du H, Zhao Z, Dong Y, He S, Shao R, Wang Y, Han W, Wang X, Zhu Y, Tengdan Capsule Prevents Hypertensive Kidney Damage in SHR by Inhibiting Periostin-Mediated Renal Fibrosis. Front Pharmacol, 12():638298(2021) [pubmed] |
Keyword List
submitter keyword: Teng Dan Capsule |
hypertension-induced Kidney damage |
Periostin |
TGFβ/SMAD signaling pathway |
inflammatory response |
human kidney HEK293 cells |
Contact List
Yan ZHU |
contact affiliation | Tianjin University of Traditional Chinese Medicine |
contact email | yanzhu.harvard@icloud.com |
lab head | |
Xiaoli DU |
contact affiliation | Tianjin University of Traditional Chinese Medicine |
contact email | 48121567@qq.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD024102
- Label: PRIDE project
- Name: Tengdan Capsule Prevents Hypertensive Kidney Damage in SHR by Inhibiting Periostin-mediated Renal Fibrosis