PXD023938 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic analysis of human sepsis monocytes |
Description | In this project we performed a comprehensive exploration of monocyte molecular responses in a cohort of patients with septic shock via label-free shotgun proteomics. We enrolled adult (≥18 years old) patients with sepsis from community-acquired infections, diagnosed according to the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) criteria. Blood samples were obtained within the first 72 hours from the diagnosis of sepsis (sepsis phase) and on de day before ICU discharge (recovery phase). The Control group consisted of age matched healthy volunteers. We excluded subjects with AIDS, advanced cancer, hematological diseases, and pregnancy. |
HostingRepository | PRIDE |
AnnounceDate | 2021-09-07 |
AnnouncementXML | Submission_2021-09-07_04:04:37.787.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Monique Trugilho |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue; deamidated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-02-02 01:54:48 | ID requested | |
⏵ 1 | 2021-09-07 04:04:38 | announced | |
Publication List
de Azambuja Rodrigues PM, Valente RH, Brunoro GVF, Nakaya HTI, Ara, ú, jo-Pereira M, Bozza PT, Bozza FA, Trugilho MRO, Proteomics reveals disturbances in the immune response and energy metabolism of monocytes from patients with septic shock. Sci Rep, 11(1):15149(2021) [pubmed] |
Keyword List
submitter keyword: Sepsis, Septic shock, infection, human, monocyte, blood |
Contact List
Monique Trugilho |
contact affiliation | Center for Technological Development in Health (CDTS) - FIOCRUZ, Brazil. |
contact email | mrotrugilho@hotmail.com |
lab head | |
Monique Trugilho |
contact affiliation | Center for Technological Development in Health (CDTS/FIOCRUZ) |
contact email | mrotrugilho@hotmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD023938 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD023938
- Label: PRIDE project
- Name: Proteomic analysis of human sepsis monocytes