PXD023900-2

PXD023900 is an original dataset announced via ProteomeXchange.

Title	Proteomic signatures in chronic obstructive pulmonary disease emphysematous phenotype
Description	Chronic obstructive pulmonary disease (COPD) is a highly heterogeneous disease. Emphysematous phenotype is a type of most common and critical phenotype, which is characterized by progressive lung destruction and poor prognosis. However, the underlying mechanism of this structural damage has not been completely elucidated. A total of 12 patients with COPD emphysematous phenotype (COPD-E) and 9 patients with COPD non-emphysematous phenotype (COPD-NE) were enrolled to determine differences in differential abundant protein (DAP) expression between both groups. Quantitative tandem mass tag-based proteomics was performed on lung tissue samples of all patients.
HostingRepository	iProX
AnnounceDate	2021-01-31
AnnouncementXML	Submission_2021-08-03_01:01:54.443.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Li Zhao
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-31 21:13:14	ID requested
1	2021-06-21 19:55:53	announced
⏵ 2	2021-08-03 01:01:55	announced	2021-08-03: Update publication information.

Bai S, Ye R, Wang C, Sun P, Wang D, Yue Y, Wang H, Wu S, Yu M, Xi S, Zhao L, Identification of Proteomic Signatures in Chronic Obstructive Pulmonary Disease Emphysematous Phenotype. Front Mol Biosci, 8():650604(2021) [pubmed]

submitter keyword: Human, Lung tissue, LC-MSMS, COPD emphysematous phenotype

Li Zhao
contact affiliation	Shengjing Hospital of China Medical University
contact email	zhaol_sj@163.com
lab head
Li Zhao
contact affiliation	Shengjing Hospital of China Medical University
contact email	zhaol_sj@163.com
dataset submitter

iProX dataset URI