PXD023758 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Human TRPV4 LC-MS protein interactor screen |
Description | TRPV4 is a cell surface-expressed calcium-permeable cation channel that mediates cell-specific effects on cellular morphology and function. Dominant missense mutations of TRPV4 cause various forms of inherited neuropathy, but the pathogenic mechanisms are unknown. Using an unbiased screen, we sought to identify novel TRPV4 interactors that may be relevant to disease pathogenesis. |
HostingRepository | PRIDE |
AnnounceDate | 2021-01-29 |
AnnouncementXML | Submission_2021-01-29_04:45:13.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD023758 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Brett McCray |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2021-01-22 06:51:37 | ID requested | |
⏵ 1 | 2021-01-29 04:45:14 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: TRPV4, HEK-293T, CMT2C |
Contact List
Charlotte Jane Sumner |
contact affiliation | Department of Neurology, Johns Hopkins School of Medicine |
contact email | csumner1@jhmi.edu |
lab head | |
Brett McCray |
contact affiliation | Johns Hopkins School of Medicine |
contact email | bmccray3@jhmi.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/01/PXD023758 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD023758
- Label: PRIDE project
- Name: Human TRPV4 LC-MS protein interactor screen