PXD023753-1

PXD023753 is an original dataset announced via ProteomeXchange.

Title	RGS10L phosphorylation site determination Bottom-Up
Description	RGS10L phosphorylatin site was determined. Trypsin is not good for generating a peptide containing the potential site, and the initial study was done using the intact protein. From the Top-Down study, the phosphorylatin site of the A->S variant was ambiguous. The firnal confirmation was done using AspN digest.
HostingRepository	PRIDE
AnnounceDate	2021-11-03
AnnouncementXML	Submission_2021-11-03_02:27:35.290.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD023753
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Motoshi Suzuki
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2021-01-22 06:42:53	ID requested
⏵ 1	2021-11-03 02:27:36	announced

Chinn IK, Xie Z, Chan EC, Nagata BM, Koval A, Chen WS, Zhang F, Ganesan S, Hong DN, Suzuki M, Nardone G, Moore IN, Katanaev VL, Balazs AE, Liu C, Lupski JR, Orange JS, Druey KM, Short stature and combined immunodeficiency associated with mutations in RGS10. Sci Signal, 14(693):(2021) [pubmed]

submitter keyword: RGS10L, Bottom-Up, phosphorylation

Kirk M. Druey
contact affiliation	Lung and Vascular Inflammation Section, Laboratory of Allergic Diseases, NIAID/NIH Bethesda, MD 20892, USA
contact email	kdruey@niaid.nih.gov
lab head
Motoshi Suzuki
contact affiliation	NIAID
contact email	motoshi.suzuki@nih.gov
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD023753
     1. Label: PRIDE project
     2. Name: RGS10L phosphorylation site determination Bottom-Up