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PXD023400 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMechanism of disaggregation of Tau fibrils in vivo
DescriptionThe interactome of fibrillar aggregates of the Tau repeat domain fused to YFP (TauRD-Y) was analyzed in HEK293T cells using SILAC. TauRD-Y was immunoprecipitated with anti-GFP antibody from lysates of SILAC-labeled cells expressing TauRD-Y in soluble form (light labeled; L), from cells containing aggregated TauRD-Y in nucleus and cytosol (medium labeled; M), and from cells containing aggregated TauRD-Y mainly localized to the cytoosl (heavy-labeled; H).
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02021-01-04 04:02:22ID requested
12022-12-09 07:06:52announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Amyloid fibrils
AAA+ chaperones
prion-like aggregate spreading
Contact List
F. UlrichHartl
contact affiliationMax-Planck Institute of Biochemistry, Department of Cellular Biochemistry
contact emailuhartl@biochem.mpg.de
lab head
contact affiliationMax-Planck Institute of Biochemistry, Department of Cellular Biochemistry
contact emailrkoerner@biochem.mpg.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
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