PXD023166 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic analysis of human microglia cells (HMC3) stimulated with anti-inflammatory cytokines using serum-enriched culture conditions |
Description | The immune functions of microglia in the brain are compromised in the presence of tumors that have the ability to “hijack” their pro-inflammatory nature by sending out signals that promote cancer progression. To analyze the tumor-supportive microglia phenotype, human microglia cells (HMC3) were treated with anti-inflammatory cytokines in serum-enriched cell culture media, and analyzed by LC-MS/MS using an Orbitrap QE instrument. |
HostingRepository | PRIDE |
AnnounceDate | 2021-10-07 |
AnnouncementXML | Submission_2021-10-07_00:07:49.441.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Iulia M. Lazar |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; acetylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-12-16 01:31:32 | ID requested | |
1 | 2021-10-06 16:02:08 | announced | |
⏵ 2 | 2021-10-07 00:07:50 | announced | 2021-10-07: Updated project metadata. |
Publication List
Ahuja S, Lazar IM, Systems-Level Proteomics Evaluation of Microglia Response to Tumor-Supportive Anti-Inflammatory Cytokines. Front Immunol, 12():646043(2021) [pubmed] |
10.3389/FIMMU.2021.646043; |
Keyword List
submitter keyword: HMC3, cytokines, tumor,Microglia |
Contact List
Iulia Lazar |
contact affiliation | Virginia Tech |
contact email | malazar@vt.edu |
lab head | |
Iulia M. Lazar |
contact affiliation | Virginia Tech |
contact email | malazar@vt.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/10/PXD023166 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD023166
- Label: PRIDE project
- Name: Proteomic analysis of human microglia cells (HMC3) stimulated with anti-inflammatory cytokines using serum-enriched culture conditions