PXD023138-2

PXD023138 is an original dataset announced via ProteomeXchange.

Title	SARS-CoV-2 S protein ACE2 interaction reveals novel allosteric targets
Description	SARS-CoV-2 spike protein binding to receptor ACE2 allosterically enhances furin proteolysisat distal S1/S2 cleavage sites
HostingRepository	PRIDE
AnnounceDate	2021-08-09
AnnouncementXML	Submission_2021-08-09_04:23:53.007.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Raghuvamsi Palur
SpeciesList	scientific name: Severe acute respiratory syndrome coronavirus 2; NCBI TaxID: 2697049;
ModificationList	No PTMs are included in the dataset
Instrument	Synapt MS

Revision	Datetime	Status	ChangeLog Entry
0	2020-12-15 01:41:47	ID requested
1	2021-08-09 02:32:50	announced
⏵ 2	2021-08-09 04:23:53	announced	2021-08-09: Updated project metadata.
3	2024-10-22 05:24:26	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

ProteomeXchange project tag: Covid-19

submitter keyword: SARS-CoV-2, Spike, MD simulations, HDX-MS

Ganesh S Anand
contact affiliation	Current affiliation: Department of Chemistry, The Pennsylvania State University, 104 Chemistry Building, University Park, PA
contact email	gsa5089@psu.edu
lab head
Raghuvamsi Palur
contact affiliation	National University of Singapore
contact email	e0225103@u.nus.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD023138

PRIDE project URI

• PRIDE
  1. PXD023138
     1. Label: PRIDE project
     2. Name: SARS-CoV-2 S protein ACE2 interaction reveals novel allosteric targets