PXD022671-1

PXD022671 is an original dataset announced via ProteomeXchange.

Title	Effects of TDP-43 overexpression on neuron proteome and morphology in vitro
Description	Primary neuronal cultures were prepared from transgenic mice overexpressing wildtype human TDP-43 under the control of the prion promoter (hTDP-43Prp).
HostingRepository	PRIDE
AnnounceDate	2026-06-29
AnnouncementXML	Submission_2026-06-28_19:11:53.638.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Richard Wilson
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-11-23 09:09:43	ID requested
⏵ 1	2026-06-28 19:11:54	announced

10.1016/j.mcn.2021.103627;

Atkinson RAK, Fair HL, Wilson R, Vickers JC, King AE, Effects of TDP-43 overexpression on neuron proteome and morphology in vitro. Mol Cell Neurosci, 114():103627(2021) [pubmed]

submitter keyword: proteomics,TDP-43, ALS, FTD, neuron morphology

Dr Richard Wilson
contact affiliation	Proteomics facility, Central Science Laboratory, University of Tasmania
contact email	richard.wilson@utas.edu.au
lab head
Richard Wilson
contact affiliation	University of Tasmania
contact email	richard.wilson@utas.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD022671

PRIDE project URI

• PRIDE
  1. PXD022671
     1. Label: PRIDE project
     2. Name: Effects of TDP-43 overexpression on neuron proteome and morphology in vitro