PXD022578-1

PXD022578 is an original dataset announced via ProteomeXchange.

Title	Insights into the modes of action of tritium on zebrafish, Danio rerio, early-life stages, using proteomic analyses
Description	Tritium is an ubiquist radionuclide which can be found in the environment due to natural and anthropogenic activities, particularly in aquatic ecosystems. In this context, tritium effects on aquatic species such as fish have to be characterized. HTO (tritiated water) effects were therefore investigated in zebrafish, Danio rerio, a common model in toxicology and ecotoxicology with a fully sequenced genome. Experiments were conducted on early life stages. Larvae were exposed to 0.4 and 4 mGy/h of HTO until 10 days post fertilization. Tritium internalization was quantified and effects were investigated using a proteomic analysis. The global analysis of the proteome was performed after protein extraction at 7 and 10 dpf on zebrafish eggs exposed from 3 hpf to 10 dpf.
HostingRepository	PRIDE
AnnounceDate	2024-08-29
AnnouncementXML	Submission_2024-08-29_06:42:41.169.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Luc Camoin
SpeciesList	scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: 7955;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-11-17 01:54:11	ID requested
⏵ 1	2024-08-29 06:42:42	announced
2	2024-10-22 06:56:59	announced	2024-10-22: Updated project metadata.

10.1016/j.jenvrad.2023.107141;

Arcanjo C, Frelon S, Armant O, Camoin L, Audebert S, Camilleri V, Cavali, é I, Adam-Guillermin C, Gagnaire B, Insights into the modes of action of tritium on the early-life stages of zebrafish, Danio rerio, using transcriptomic and proteomic analyses. J Environ Radioact, 261():107141(2023) [pubmed]

submitter keyword: Tritium

zebrafish Danio rerio

early-life stages

proteomics

Luc Camoin
contact affiliation	Marseille Protéomique, Inserm, CNRS, IPC
contact email	luc.camoin@inserm.fr
lab head
Luc Camoin
contact affiliation	Life Sciences
contact email	luc.camoin@inserm.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD022578

PRIDE project URI

• PRIDE
  1. PXD022578
     1. Label: PRIDE project
     2. Name: Insights into the modes of action of tritium on zebrafish, Danio rerio, early-life stages, using proteomic analyses