PXD022541-1

PXD022541 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic analysis reveals critical immunomolecular mechanisms in macrophage anti-tuberculosis processes
Description	Tuberculosis infection activates the autoimmune system. However, the role of autoimmunity after Mycobacterium tuberculosis infection is unclear. In this study, liquid chromatography-tandem mass spectrometry (LC-MS/MS) combined with tandem mass spectrometry (TMT) was used to perform proteomic analysis of five spinal tuberculosis and five protruding disc tissue samples. The identification of key molecular mechanisms provides a molecular target for future treatment of spinal tuberculosis, which may significantly improve patients' quality of life and prognosis.
HostingRepository	PRIDE
AnnounceDate	2024-10-08
AnnouncementXML	Submission_2024-10-08_11:40:42.708.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xinli Zhan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	6410 Triple Quadrupole LC/MS

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-11-16 03:38:25	ID requested
⏵ 1	2024-10-08 11:40:43	announced

Publication List

Xu G, Xue J, Jiang J, Liang T, Yao Y, Liao S, Chen T, Li H, Liu C, Zhan X, Proteomic analysis reveals critical molecular mechanisms involved in the macrophage anti-spinal tuberculosis process. Tuberculosis (Edinb), 126():102039(2021) [pubmed]
10.1016/j.tube.2020.102039;

Xu G, Xue J, Jiang J, Liang T, Yao Y, Liao S, Chen T, Li H, Liu C, Zhan X, Proteomic analysis reveals critical molecular mechanisms involved in the macrophage anti-spinal tuberculosis process. Tuberculosis (Edinb), 126():102039(2021) [pubmed]

10.1016/j.tube.2020.102039;

Keyword List

submitter keyword: Spinal tuberculosis, proteomics, immunology, macrophages, bioinformatics

submitter keyword: Spinal tuberculosis, proteomics, immunology, macrophages, bioinformatics

Contact List

Xinli Zhan
contact affiliation	The First Affiliated Hospital of Guangxi Medical University
contact email	xgygxmu136@163.com
lab head
Xinli Zhan
contact affiliation	The First Affiliated Hospital of Guangxi Medical University
contact email	xgygxmu136@163.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/01/PXD022541
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/01/PXD022541

PRIDE project URI

Repository Record List

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