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PXD022541-1

PXD022541 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis reveals critical immunomolecular mechanisms in macrophage anti-tuberculosis processes
DescriptionTuberculosis infection activates the autoimmune system. However, the role of autoimmunity after Mycobacterium tuberculosis infection is unclear. In this study, liquid chromatography-tandem mass spectrometry (LC-MS/MS) combined with tandem mass spectrometry (TMT) was used to perform proteomic analysis of five spinal tuberculosis and five protruding disc tissue samples. The identification of key molecular mechanisms provides a molecular target for future treatment of spinal tuberculosis, which may significantly improve patients' quality of life and prognosis.
HostingRepositoryPRIDE
AnnounceDate2024-10-08
AnnouncementXMLSubmission_2024-10-08_11:40:42.708.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterXinli Zhan
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
Instrument6410 Triple Quadrupole LC/MS
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-11-16 03:38:25ID requested
12024-10-08 11:40:43announced
Publication List
Xu G, Xue J, Jiang J, Liang T, Yao Y, Liao S, Chen T, Li H, Liu C, Zhan X, Proteomic analysis reveals critical molecular mechanisms involved in the macrophage anti-spinal tuberculosis process. Tuberculosis (Edinb), 126():102039(2021) [pubmed]
10.1016/j.tube.2020.102039;
Keyword List
submitter keyword: Spinal tuberculosis, proteomics, immunology, macrophages, bioinformatics
Contact List
Xinli Zhan
contact affiliationThe First Affiliated Hospital of Guangxi Medical University
contact emailxgygxmu136@163.com
lab head
Xinli Zhan
contact affiliationThe First Affiliated Hospital of Guangxi Medical University
contact emailxgygxmu136@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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