PXD022506-1

PXD022506 is an original dataset announced via ProteomeXchange.

Title	Discovery of biomarkers in radioresistant MCF7R breast cancer xenografts
Description	Radioresistance of tumors is not completely understood. Our previous studies have shown that MCF-7 breast cancer cell line exposed to 6 Gy and allowed to recover for 7 days (D7-6G) developed radio-resistance. In this study, we have tested the ability of these cells to form tumors in SCID mice and characterized these tumors by proteomic analyses. Untreated (MCF-C) and D7-6G cells (MCF-R) were injected s.c. in SCID mice and tumor growth monitored. On day 18, the mice were sacrificed and proteins were extracted from tumor tissues label free proteomic analyses was carried out by LC-MS.
HostingRepository	PRIDE
AnnounceDate	2021-01-04
AnnouncementXML	Submission_2021-01-04_01:05:34.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Bhavani Shankar
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2020-11-13 03:13:20	ID requested
⏵ 1	2021-01-04 01:05:34	announced

Yadav P, Pandey VK, Shankar BS, signaling and metabolism. Cell Biol Int, 45(4):804-819(2021) [pubmed]

submitter keyword: breast cancer, radioresistance, xenografts, MCF7

Dr. Bhavani Shankar
contact affiliation	Head, Immunology Section, Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre
contact email	bshankar@barc.gov.in
lab head
Bhavani Shankar
contact affiliation	Bhabha Atomic Research Centre
contact email	bshankar@barc.gov.in
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/01/PXD022506

PRIDE project URI

• PRIDE
  1. PXD022506
     1. Label: PRIDE project
     2. Name: Discovery of biomarkers in radioresistant MCF7R breast cancer xenografts