PXD022345 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Effect of fluvastatin-treatment on the proteome and phosphor-proteome in metastatic pancreatic cancer cells |
Description | Fluvastatin has been identified as novel inhibitors of metastasis in pancreatic cancer. In multiple in vivo and in vitro experiments the compounds phenotypic effects was validated. Since under drug treatment the transcriptomic changes in examined cell lines were rather small, we expected the underlying mechanistic effect to be on the level of the proteome and more importantly the phospho-proteome. To evaluate this assumption we performed label-free full proteome and phosphoproteomics experiments on Fluvastatin treated ASPC1 cells. |
HostingRepository | PRIDE |
AnnounceDate | 2021-11-29 |
AnnouncementXML | Submission_2021-11-29_06:21:53.051.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Farnusch Kaschani |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue; monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-11-04 04:59:49 | ID requested | |
⏵ 1 | 2021-11-29 06:21:53 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: pancreatic cancer, statins, fluvastatin |
Contact List
Farnusch Kaschani |
contact affiliation | Farnusch Kaschani, Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany |
contact email | farnusch.kaschani@uni-due.de |
lab head | |
Farnusch Kaschani |
contact affiliation | University Duisburg-Essen |
contact email | farnusch.kaschani@uni-due.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD022345
- Label: PRIDE project
- Name: Effect of fluvastatin-treatment on the proteome and phosphor-proteome in metastatic pancreatic cancer cells