PXD022149-1

PXD022149 is an original dataset announced via ProteomeXchange.

Title	Ceragenins and antimicrobial peptides kill bacteria through distinct mechanisms
Description	Ceragenins are a family of synthetic amphipathic molecules designed to mimic the properties of naturally-occurring cationic antimicrobial peptides (CAMPs). Although ceragenins have potent antimicrobial activity, whether their mode of action is similar to that of CAMPs has remained elusive. Here we report the results of a comparative study of the bacterial responses to two well-studied CAMPs, LL37 and colistin, and two ceragenins with related structures, CSA13 and CSA13.
HostingRepository	PRIDE
AnnounceDate	2022-01-10
AnnouncementXML	Submission_2022-01-10_10:45:36.906.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jonathan Budzik
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-10-23 01:25:35	ID requested
⏵ 1	2022-01-10 10:45:37	announced

Dataset with its publication pending

submitter keyword: Antibiotics, Gram-negative, Gram-positive, mycobacteria, CSA

Jeffery S Coox
contact affiliation	Molecular and Cell Biology University of California, Berkeley
contact email	jeff.cox@berkeley.edu
lab head
Jonathan Budzik
contact affiliation	UCSF
contact email	jonathan.budzik2@ucsf.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/01/PXD022149

PRIDE project URI

• PRIDE
  1. PXD022149
     1. Label: PRIDE project
     2. Name: Ceragenins and antimicrobial peptides kill bacteria through distinct mechanisms