PXD022054-1

PXD022054 is an original dataset announced via ProteomeXchange.

Title	Medieval birth girdle stains LC-MSMS
Description	This project applied a dry non-invasive method to detect palaeoproteomic evidence from stained manuscripts. The manuscript analysed in this study is a medieval parchment birth girdle (Wellcome Collection Western MS. 632) made in England and thought to be used by pregnant women while giving birth. Using a dry non-invasive sampling method we were able to extract both human and non-human peptides from the stains, including evidence for the use of honey, cereals, ovicaprine milk and legumes. In addition, a large number of human peptides were detected on the birth roll, many of which are found in cervico-vaginal fluid. This suggests that the birth roll was actively used during childbirth. This study is the first to extract and analyse non-collagenous peptides from a parchment document using a dry non-invasive sampling method and demonstrates the potential of this type of analysis for stained manuscripts, providing direct biomolecular evidence for active use.
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-09_10:16:05.385.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sarah Fiddyment
SpeciesList	scientific name: Apis mellifera (Honeybee); NCBI TaxID: 7460; scientific name: Ovis aries; NCBI TaxID: 9940; scientific name: Pisum sativum (Garden pea); NCBI TaxID: 3888; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Vicia faba; NCBI TaxID: 3906;
ModificationList	monohydroxylated residue; deamidated residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2020-10-18 23:45:15	ID requested
⏵ 1	2021-09-09 10:16:07	announced

Fiddyment S, Goodison NJ, Brenner E, Signorello S, Price K, Collins MJ, Girding the loins? Direct evidence of the use of a medieval English parchment birthing girdle from biomolecular analysis. R Soc Open Sci, 8(3):202055(2021) [pubmed]

submitter keyword: LC-MSMS, Birth, Medieval

Matthew James Collins
contact affiliation	McDonald Professor of Palaeoproteomics, McDonald Institute for Archaeological Research, University of Cambridge, UK
contact email	matthew@palaeome.org
lab head
Sarah Fiddyment
contact affiliation	University of Cambridge
contact email	sarah.fiddyment@palaeome.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD022054

PRIDE project URI

• PRIDE
  1. PXD022054
     1. Label: PRIDE project
     2. Name: Medieval birth girdle stains LC-MSMS