PXD021803-1

PXD021803 is an original dataset announced via ProteomeXchange.

Title	Mitotic activity shapes stage-specific histone modification profiles during Xenopus embryogenesis
Description	Here we investigate the possible relationship between the propagation of epigenetic information and the developmental cell proliferation during Xenopus embryogenesis. We systemically inhibited cell proliferation during the G1/S-transition in gastrula embryos and followed their development until the tadpole stage. We quantified by mass spectrometry the abundance of a large set of histone modification states, which reflects the developmental maturation of the embryonic epigenome.
HostingRepository	PRIDE
AnnounceDate	2024-10-07
AnnouncementXML	Submission_2024-10-07_13:36:09.931.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Daniil Pokrovsky
SpeciesList	scientific name: Xenopus laevis (African clawed frog); NCBI TaxID: 8355;
ModificationList	monomethylated residue; phosphorylated residue; acetylated residue; dimethylated residue; N6,N6,N6-trimethyl-L-lysine
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-10-04 23:20:37	ID requested
⏵ 1	2024-10-07 13:36:10	announced
2	2024-10-22 05:24:26	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Histone modification

epigenetics

cell cycle

Xenopus

development

Ralph AW Rupp
contact affiliation	Molecular Biology, Ludwig-Maximilians-Universitat Munchen
contact email	ralph.rupp@bmc.med.lmu.de
lab head
Daniil Pokrovsky
contact affiliation	Ludwig Maximilian University of munich, BMC
contact email	D.Pokrovsky@med.uni-muenchen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD021803

PRIDE project URI

• PRIDE
  1. PXD021803
     1. Label: PRIDE project
     2. Name: Mitotic activity shapes stage-specific histone modification profiles during Xenopus embryogenesis