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PXD021803-1

PXD021803 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMitotic activity shapes stage-specific histone modification profiles during Xenopus embryogenesis
DescriptionHere we investigate the possible relationship between the propagation of epigenetic information and the developmental cell proliferation during Xenopus embryogenesis. We systemically inhibited cell proliferation during the G1/S-transition in gastrula embryos and followed their development until the tadpole stage. We quantified by mass spectrometry the abundance of a large set of histone modification states, which reflects the developmental maturation of the embryonic epigenome.
HostingRepositoryPRIDE
AnnounceDate2024-10-07
AnnouncementXMLSubmission_2024-10-07_13:36:09.931.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDaniil Pokrovsky
SpeciesList scientific name: Xenopus laevis (African clawed frog); NCBI TaxID: 8355;
ModificationListmonomethylated residue; phosphorylated residue; acetylated residue; dimethylated residue; N6,N6,N6-trimethyl-L-lysine
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-10-04 23:20:37ID requested
12024-10-07 13:36:10announced
22024-10-22 05:24:26announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Histone modification
epigenetics
cell cycle
Xenopus
development
Contact List
Ralph AW Rupp
contact affiliationMolecular Biology, Ludwig-Maximilians-Universitat Munchen
contact emailralph.rupp@bmc.med.lmu.de
lab head
Daniil Pokrovsky
contact affiliationLudwig Maximilian University of munich, BMC
contact emailD.Pokrovsky@med.uni-muenchen.de
dataset submitter
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Dataset FTP location
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