PXD021487-1

PXD021487 is an original dataset announced via ProteomeXchange.

Title	Lipid and protein profiles associated to human osteoarthritis type 2 diabetes phenotype
Description	Osteoarthritis (OA) is a multifactorial pathology which comprises a wide range of distinct phenotypes. The characterization of the different molecular profiles associated to each phenotype can improve the classification of OA for a better personalized medicine. Within the metabolic syndrome phenotype, OA can co-exist with type 2 diabetes (TD2) disease. This study was undertaken to investigate lipidomic and proteomic differences between human OA and OA/TD2 cartilage through a multimodal mass spectrometry approach.
HostingRepository	PRIDE
AnnounceDate	2021-04-20
AnnouncementXML	Submission_2021-04-20_05:22:47.562.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	freek bouwman
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-09-15 05:05:53	ID requested
⏵ 1	2021-04-20 05:22:48	announced

Eveque-Mourroux MR, Emans PJ, Boonen A, Claes BSR, Bouwman FG, Heeren RMA, Cillero-Pastor B, Heterogeneity of Lipid and Protein Cartilage Profiles Associated with Human Osteoarthritis with or without Type 2 Diabetes Mellitus. J Proteome Res, 20(5):2973-2982(2021) [pubmed]

ProteomeXchange project tag: Biology/Disease-Driven Human Proteome Project (B/D-HPP), Diabetes (B/D-HPP), Human Proteome Project

submitter keyword: Human osteoarthritis type 2 diabete

Berta Cillero Pastor
contact affiliation	M4i Maastricht University
contact email	b.cilleropastor@maastrichtuniversity.nl
lab head
freek bouwman
contact affiliation	Human Biology
contact email	freek.bouwman@maastrichtuniversity.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD021487

PRIDE project URI

• PRIDE
  1. PXD021487
     1. Label: PRIDE project
     2. Name: Lipid and protein profiles associated to human osteoarthritis type 2 diabetes phenotype