PXD021254 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative phosphoproteomics of chronic sunitinib treated renal cell carcinoma 786-O cells with GPR30 agonist G-1 |
Description | In this project, we generated chronic sunitinib-treated 786-O cell, a renal cell carcinoma cell line. In order to investigate the possible effect of GPR30 agonist, G-1, on the growth-inhibtion related signaling pathways, we treated either parental both parental and chronic sunitinib-treated 786-O cells were treated either by vehicle-only (i.e. 0.1% DMSO) or 2 μM G-1 for 48 h. Therefore, there were three groups for comparison, including G-1 treatment (G-1 vs. parental), chronic sunitinib-treatment (SunR vs. parental), and G-1 treatment in SunR cells (SunR&G-1 vs. parental). |
HostingRepository | PRIDE |
AnnounceDate | 2021-04-28 |
AnnouncementXML | Submission_2021-04-27_22:05:58.738.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Wei-Chi Ku |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | LTQ Orbitrap XL |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-09-01 04:33:24 | ID requested | |
1 | 2021-04-27 21:06:41 | announced | |
⏵ 2 | 2021-04-27 22:05:59 | announced | 2021-04-28: Updated project metadata. |
Publication List
Chen SK, Wang YC, Lin TY, Wu HJ, Huang CJ, Ku WC, G-Protein-coupled Estrogen Receptor 1 Agonist G-1 Perturbs Sunitinib Resistance-related Phosphoproteomic Signatures in Renal Cell Carcinoma. Cancer Genomics Proteomics, 18(3):207-220(2021) [pubmed] |
10.21873/CGP.20253; |
Keyword List
submitter keyword: renal cell carcinoma, sunitinib, GPR30 |
Contact List
Wei-Chi Ku |
contact affiliation | School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei, Taiwan |
contact email | 089052@mail.fju.edu.tw |
lab head | |
Wei-Chi Ku |
contact affiliation | Fu Jen Catholic University |
contact email | 089052@mail.fju.edu.tw |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD021254 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD021254
- Label: PRIDE project
- Name: Quantitative phosphoproteomics of chronic sunitinib treated renal cell carcinoma 786-O cells with GPR30 agonist G-1