PXD021210 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative TMT proteomics of brainstem in spontaneously hypertensive rats |
Description | The brainstem, the core of the central nervous system, plays a vital role in controlling arterial blood pressure and its elevation of hypertension subtypes, especially essential hypertension. Integrative metabolic and proteomic profiling was performed on the brainstem samples of 11-week-old spontaneously hypertensive rats (SHRs) and age-matched normotensive Wistar rats, using hydrophilic interaction liquid chromatography-quadrupole/time-of-flight mass spectrometry (HILIC-Q/TOFMS) and nano-liquid chromatography-high-resolution-mass spectrometry (nano-LC-high-resolution-MS) combined with quantitative tandem mass tags (TMT). |
HostingRepository | PRIDE |
AnnounceDate | 2020-09-24 |
AnnouncementXML | Submission_2020-09-24_00:52:33.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Cheng Yu |
SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-08-31 01:19:08 | ID requested | |
⏵ 1 | 2020-09-24 00:52:34 | announced | |
Publication List
Cheng Y, Sun D, Zhu B, Zhou W, Lv C, Kou F, Wei H, Integrative Metabolic and Proteomic Profiling of the Brainstem in Spontaneously Hypertensive Rats. J Proteome Res, 19(10):4114-4124(2020) [pubmed] |
Keyword List
submitter keyword: Brainstem, spontaneously hypertensive rats/SHR rats, quantitative proteome, TMT |
Contact List
Yu Cheng |
contact affiliation | Institute of Interdisciplinary Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China |
contact email | ycheng_16@163.com |
lab head | |
Cheng Yu |
contact affiliation | Shanghai Jiao Tong University |
contact email | ycheng_16@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD021210
- Label: PRIDE project
- Name: Quantitative TMT proteomics of brainstem in spontaneously hypertensive rats