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PXD020939-1

PXD020939 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative LC-MS/MS Proteomics of paediatric human liver microsomes (set 2)
DescriptionWe report label-free quantification of xenobiotic metabolizing enzymes (XME), transporters, redox enzymes, proteases and nucleases in 24 human liver microsomal samples. More than 3500 proteins were identified and quantified. These data can be used in physiologically based pharmacokinetic models to predict appropriate drug doses for a wide variety of drugs.
HostingRepositoryPRIDE
AnnounceDate2021-09-09
AnnouncementXMLSubmission_2021-09-08_23:58:06.282.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJill Barber
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-08-17 00:18:46ID requested
12021-09-08 23:58:07announced
Publication List
Al-Majdoub ZM, Achour B, Couto N, Howard M, Elmorsi Y, Scotcher D, Alrubia S, El-Khateeb E, Vasilogianni AM, Alohali N, Neuhoff S, Schmitt L, Rostami-Hodjegan A, Barber J, Mass spectrometry-based abundance atlas of ABC transporters in human liver, gut, kidney, brain and skin. FEBS Lett, 594(23):4134-4150(2020) [pubmed]
Keyword List
submitter keyword: Human, paediatric livers, LC-MS/MS, quantitative proteomics
Contact List
Jill Barber
contact affiliationCentre for Applied Pharmacokinetic Research, School of Health Sciences, The University of Manchester, UK
contact emailjill.barber@manchester.ac.uk
lab head
Jill Barber
contact affiliationThe University of Manchester
contact emailJill.barber@manchester.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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