PXD020903 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Alteration of protein expression and spliceosome pathway activity during Barrett’s carcinogenesis. |
Description | Esophageal adenocarcinoma (EAC) is a common and aggressive type of cancer and Barrett’s esophagus (BE) is a known precursor lesion and the strongest risk factor for EAC. Prediction of risk is currently based on histologic examination which is challenged by problems such as inter-observer variability due to high heterogeneity of the dysplastic tissue. Molecular markers might offer an additional way to understand carcinogenesis and improve diagnosis and eventually treatment. . |
HostingRepository | PRIDE |
AnnounceDate | 2021-09-09 |
AnnouncementXML | Submission_2021-09-09_04:17:32.734.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD020903 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Christoph Stingl |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-08-13 22:49:26 | ID requested | |
⏵ 1 | 2021-09-09 04:17:33 | announced | |
Publication List
Stingl C, Bureo Gonzalez A, G, ü, zel C, Phoa KYN, Doukas M, Breimer GE, Meijer SL, Bergman JJ, Luider TM, Alteration of protein expression and spliceosome pathway activity during Barrett's carcinogenesis. J Gastroenterol, 56(9):791-807(2021) [pubmed] |
Keyword List
submitter keyword: Barrett’s esophagus, dysplastia, adenocarcinoma, epithelial cells, laser capture micro-dissection, bottom-up proteomics, mass spectrometry |
Contact List
Theo M. Luider |
contact affiliation | ErasmusMC, Dept. of Neurology, Laboratory Clinical & Cancer Proteomics, Rotterdam, The Netherlands |
contact email | t.luider@erasmusmc.nl |
lab head | |
Christoph Stingl |
contact affiliation | Erasmus MC Rotterdam Department of Neurology |
contact email | c.stingl@erasmusmc.nl |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020903
- Label: PRIDE project
- Name: Alteration of protein expression and spliceosome pathway activity during Barrett’s carcinogenesis.