PXD020770 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteome and Phosphoproteome of AhR-dependent non-genomic signaling in endotoxin-activated macrophages |
Description | Emerging studies revealed an immunomodulatory role of the Aryl hydrocarbon receptor (AhR), a receptor sensing environmental contaminants, and involved in their detoxification. Besides its function as a transcription factor, AhR can participate in non-genomic signaling through ubiquitination and phosphorylation-dependent processes. In this study, a multi-PTM-omics approach, including proteome, ubiquitome, and phosphoproteome, was utilized to examine mechanisms of non-genomic AhR-signaling in endotoxin-activated monocyte-derived macrophages. This dataset entails proteome and phosphoproteome data. |
HostingRepository | PRIDE |
AnnounceDate | 2021-03-30 |
AnnouncementXML | Submission_2021-03-30_12:23:09.959.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Henning Großkopf |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-08-06 02:08:15 | ID requested | |
⏵ 1 | 2021-03-30 12:23:10 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: AhR, Macrophages, Human, Phosphoproteome, Proteome, LC-MS/MS |
Contact List
Martin von Bergen |
contact affiliation | Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ,Leipzig, Germany |
contact email | martin.vonbergen@ufz.de |
lab head | |
Henning Großkopf |
contact affiliation | Molecular Systems Biology Helmholtz Centre for Environmental Research GmbH - UFZ Leipzig, Germany |
contact email | henning.grosskopf@ufz.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020770
- Label: PRIDE project
- Name: Proteome and Phosphoproteome of AhR-dependent non-genomic signaling in endotoxin-activated macrophages