PXD020636-1

PXD020636 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	A structural mechanism for PP2A-B56alpha inhibition by CIP2A
Description	Chemical cross-linking coupled to mass spectrometry was used to study the structure of the oncoprotein CIP2A and its interaction with the B56alpha regulatory subunit of protein phosphatase 2A. Cross-linking was performed using disuccinimidyl suberate (DSS) or a combination of pimelic dihydrazide (PDH) and the coupling reagent DMTMM.
HostingRepository	PRIDE
AnnounceDate	2022-10-21
AnnouncementXML	Submission_2022-10-21_01:39:40.948.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	AlexanderLeitner
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-29 06:25:14	ID requested
⏵ 1	2022-10-21 01:39:41	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Chemical cross-linking
DSS
PDH
DMTMM
structural proteomics
protein phosphatase 2A

submitter keyword: Chemical cross-linking

DSS

PDH

DMTMM

structural proteomics

protein phosphatase 2A

Contact List

AlexanderLeitner
contact affiliation	ETH Zurich, Institute of Molecular Systems Biology, Zurich, Switzerland
contact email	leitner@imsb.biol.ethz.ch
lab head
AlexanderLeitner
contact affiliation	ETH Zurich, Institute of Molecular Systems Biology
contact email	leitner@imsb.biol.ethz.ch
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD020636
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD020636

PRIDE project URI

Repository Record List

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