PXD020530 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia |
Description | Spotted hyena (Crocuta crocuta) is the only extant species of the genus Crocuta, which once occupied a much wider range during the Pliocene and Pleistocene. However, its origin and evolutionary history is somewhat contentious due to discordances being found between morphological, nuclear, and mitochondrial data. Due to the limited molecular data from east Asian Crocuta, and the difficulty of extracting ancient DNA from this area, here we present proteomic analysis of cave hyenas from three locations in northern China. This marks the first proteomic data generated from cave hyenas, adding new molecular data to the east Asian populations. Phylogenetic analysis based on these protein sequences reveals two different groups of cave hyenas in east Asia, one of which could not be distinguished from modern spotted hyenas from northern Africa, tentatively the result of previously suggested gene flow between these lineages. With developments of instrumentation and analytical methods, proteomics holds promising potential for the phylogenetic reconstruction of ancient fauna previously thought to be unreachable using ancient DNA. |
HostingRepository | PRIDE |
AnnounceDate | 2020-10-19 |
AnnouncementXML | Submission_2020-10-19_01:13:35.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD020530 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Huiyun Rao |
SpeciesList | scientific name: Crocuta; NCBI TaxID: 9677; |
ModificationList | monohydroxylated residue; deamidated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-07-23 04:41:01 | ID requested | |
⏵ 1 | 2020-10-19 01:13:36 | announced | |
Publication List
Rao H, Yang Y, Liu J, Westbury MV, Zhang C, Shao Q, Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia. Sci Rep, 10(1):16674(2020) [pubmed] |
Keyword List
submitter keyword: Cave hyenas, Palaeoproteomics, Phylogenetic reconstruction, Northern China |
Contact List
Huiyun Rao |
contact affiliation | Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences |
contact email | raohuiyun@ivpp.ac.cn |
lab head | |
Huiyun Rao |
contact affiliation | Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences |
contact email | raohuiyun@ivpp.ac.cn |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
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- PRIDE
- PXD020530
- Label: PRIDE project
- Name: Palaeoproteomic analysis of Pleistocene cave hyenas from east Asia