PXD020468-1

PXD020468 is an original dataset announced via ProteomeXchange.

Title	Inflammaging determines health and disease in lumbar discs—evidence from differing proteomic signatures of healthy, aging, and degenerating discs
Description	The true understanding of ageing and disc degeneration (DD) is still elusive. MRI has not helped our attempts to understand the health and disease status of the discs as it reflects mainly the end morphological changes and not the changes at molecular level. Understanding degeneration at molecular level through proteomics will allow differentiation from normal ageing and also aid in the development of biomarkers for early diagnosis and preventive therapies
HostingRepository	PRIDE
AnnounceDate	2025-01-08
AnnouncementXML	Submission_2025-01-07_16:52:42.705.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD020468
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Chitraa Tangavel
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-21 04:07:04	ID requested
⏵ 1	2025-01-07 16:52:43	announced

10.6019/PXD020468;

10.1016/J.SPINEE.2019.04.023;

submitter keyword: Human, Intervertebral disc degeneration, ESI-LC-MS/MS, Inflammaging

Dr Chitraa Tangavel
contact affiliation	Research Scientist, Ganga Orthopedic Research and Education Foundation, 187, Mettupalayam Road, Kavundampalayam, Coimbatore- 641030, Tamil Nadu, India
contact email	cthangavel@gmail.com
lab head
Chitraa Tangavel
contact affiliation	Research Scientist, Ganga Orthopedic Research and Education Foundation, 187, Mettupalayam Road, Kavundampalayam, Coimbatore- 641030, Tamil Nadu, India
contact email	cthangavel@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD020468

PRIDE project URI

• PRIDE
  1. PXD020468
     1. Label: PRIDE project
     2. Name: Inflammaging determines health and disease in lumbar discs—evidence from differing proteomic signatures of healthy, aging, and degenerating discs