PXD020425-2
PXD020425 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The proteomic changes in Pseudobagrus vachelli muscle and brain induced by hypoxia |
| Description | The present NGST, TMT and Q-TOF MS platform should provide unprecedented resources to address such questions as to how hypoxic condition affects gene, miRNA, protein, and metabolite expression and changes the molecular pathways, and whether miRNAs participate in this process. For this purpose, we characterise transcriptomic, miRNAomic, proteomic and metabonomic sequencing of control- and hypoxia-treated P. vachelli muscles to elucidate the molecular mechanisms of hypoxia adaptation. We were able to find the predicted miRNA-mRNA-protein-metabolite regulatory network using bioinformatics analysis and miRNA prediction algorithms (Fig. 1). This is the first report on integrated analysis of transcriptome, miRNAome, and proteome, and metabolome in fishes and as such offers deeper insight into the hypoxia molecular mechanisms. We provide a good case study with which to analyse mRNA, miRNA, protein and metabolite expression and profile non-model fish species. |
| HostingRepository | iProX |
| AnnounceDate | 2020-07-18 |
| AnnouncementXML | Submission_2023-03-01_23:00:54.327.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Guosong Zhang |
| SpeciesList | scientific name: Tachysurus vachellii; NCBI TaxID: 175792; |
| ModificationList | TMT6plex reporter fragment |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2020-07-18 08:03:28 | ID requested | |
| 1 | 2020-07-18 08:07:50 | announced | |
| ⏵ 2 | 2023-03-01 23:00:58 | announced | 2023-03-02: Update publication information. |
Publication List
| Li J, Zhang G, Yin D, Li Y, Zhang Y, Cheng J, Zhang K, Ji J, Wang T, Jia Y, Yin S, Muscle. Mol Cell Proteomics, 21(3):100196(2022) [pubmed] |
Keyword List
| submitter keyword: Muscle and brain proteomics of Pseudobagrus fulvidraco |
Contact List
| Shaowu Yin | |
|---|---|
| contact affiliation | Nanjing normal university |
| contact email | yinshaowu@163.com |
| lab head | |
| Guosong Zhang | |
| contact affiliation | Nanjing normal university |
| contact email | 1101787529@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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