PXD020378-2

PXD020378 is an original dataset announced via ProteomeXchange.

Title	Phenotypical adaptation of Pseudomonas aeruginosa in the presence of siderophore-antibiotic conjugates during epithelial cell infection
Description	This study aims at investigating the ability of Pseudomonas aeruginosa to detect the presence of siderophore-antibiotic conjugates in an epithelial cell infection assay. We show that the presence of siderophore-antibiotic conjugates induces the transcription and expression of their corresponding transporters, indicating the bacteria are able to sense the chelators in their environment and adapt their phenotype accordingly.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:19:07.032.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Paola Cantero
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Pseudomonas aeruginosa PAO1; NCBI TaxID: 208964;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-15 06:55:49	ID requested
1	2021-02-18 05:59:30	announced
⏵ 2	2024-10-22 05:19:07	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: sideromycin, Trojan Horse antibiotic,Pseudomonas aeruginosa, siderophore, nanoLC-MS/MS, label-free analysis.

Laurence Sabatier
contact affiliation	IPHC (LSMBO-Laboratoire de Spectrométrie de Masse Bio-Organique), UMR 7178, Université de Strasbourg, CNRS
contact email	laurence.sabatier@unistra.fr
lab head
Paola Cantero
contact affiliation	IPHC (LSMBO-Laboratoire de Spectrométrie de Masse Bio-Organique), UMR 7178, Université de Strasbourg, CNRS
contact email	liz-paola.cantero-mendieta@etu.unistra.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD020378

PRIDE project URI

• PRIDE
  1. PXD020378
     1. Label: PRIDE project
     2. Name: Phenotypical adaptation of Pseudomonas aeruginosa in the presence of siderophore-antibiotic conjugates during epithelial cell infection