PXD020349-2

PXD020349 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification and quantification of cholangiocarcinoma (CCA) marker proteins from bile extracellular vesicles for non-invasive diagnosis
Description	Extracellular vesicles (EVs) including exosomes are secreted into extracellular fluids, which are found in most body fluids. Since EVs contain a number of biologically active molecules such as proteins and mRNAs, there has been increasing interest in EVs as a carrier of potential biomarkers for various diseases. We previously reported that chelating reagent enhanced the recovery rate of EVs from serum, plasma, and urine. In this study, we used bile EVs which packaged biomarker molecules secreted from CCA lesion. Then we performed proteomic analysis of EVs isolated from human bile in CCA and choledocholithiasis (biliary stone) for CCA biomarkers discovery.
HostingRepository	jPOST
AnnounceDate	2021-07-14
AnnouncementXML	Submission_2022-09-18_02:35:15.060.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ayako Kurimoto
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; alpha-amino acetylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-13 22:04:22	ID requested
1	2021-07-13 08:00:05	announced
⏵ 2	2022-09-18 02:35:15	announced	2022-09-18: Updated FTP location.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: bile, extracellular vesicles, cholangiocarcinoma

submitter keyword: bile, extracellular vesicles, cholangiocarcinoma

Contact List

Kazuya Omi
lab head
Ayako Kurimoto
contact affiliation	H.U. Group Research Institute G.K.
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000893/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000893/