PXD020286-1

PXD020286 is an original dataset announced via ProteomeXchange.

Title	Profiling of human spermatozoa glycoproteins by LC/MS/MS
Description	N-linked glycoproteins are known to be important for spermatozoa development and gametes fusion. However, little is known about detailed information of these glycoproteins, particularly the glycosylation sites and its corresponding glycan structures in human spermatozoa. In present study, an in house software coupled with LC-MS/MS analysis of intact glycopeptides was employed to establish a large scale of site-specific N-glycoproteome map in human spermatozoa. The results mapped the large-scale N-glycoproteins in human spermatozoa and interpreted the precise glycan structures with the corresponding glycosites. These presented data laid the foundation for the exploration of biological function of glycosylation on human spermatozoa and glycan structure involved male infertility.
HostingRepository	PRIDE
AnnounceDate	2023-03-04
AnnouncementXML	Submission_2023-03-04_01:45:51.241.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	MiaomiaoXin
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-09 17:23:25	ID requested
⏵ 1	2023-03-04 01:45:51	announced
2	2023-11-14 08:50:35	announced	2023-11-14: Updated project metadata.

submitter keyword: Human,LC/MS/MS, glycan structures, spermatozoa

ShishengSun
contact affiliation	Northwest University
contact email	suns@nwu.edu.cn
lab head
MiaomiaoXin
contact affiliation	College of Life Science, Northwest University, Xi’an, Shaanxi Province 710069, P. R. China
contact email	xinmiao1206@126.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD020286

PRIDE project URI

• PRIDE
  1. PXD020286
     1. Label: PRIDE project
     2. Name: Profiling of human spermatozoa glycoproteins by LC/MS/MS