PXD020192 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic Profiling of the Human Tissue and Biological Fluid Proteome |
Description | Here, we performed label-free liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) to profile the normal human proteome. In total, we analyzed 117 samples from 46 histologically normal tissues and organs at autopsy. Our high-resolution MS approach allowed for the quantification of 10,438 unique proteins. In order to expand our coverage of the human proteome, we combined our previously published biological fluid proteomic data from healthy individuals. We considered data from seven biological fluids, including urine, cerebrospinal fluid, synovial fluid, seminal plasma, sweat, cervical vaginal fluid, and nipple aspirate fluid. Overall, we generated tandem mass spectra corresponding to 13,028 unique human protein-coding genes. |
HostingRepository | PRIDE |
AnnounceDate | 2020-10-29 |
AnnouncementXML | Submission_2020-10-29_06:55:11.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Ashley Di Meo |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-07-03 17:21:31 | ID requested | |
⏵ 1 | 2020-10-29 06:55:12 | announced | |
Publication List
Di Meo A, Sohaei D, Batruch I, Alexandrou P, Prassas I, Diamandis EP, Proteomic Profiling of the Human Tissue and Biological Fluid Proteome. J Proteome Res, 20(1):444-452(2021) [pubmed] |
Keyword List
submitter keyword: mass spectrometry, LC-MS/MS, tissue proteome, biological fluid proteome, brain regions |
Contact List
Eleftherios P Diamandis |
contact affiliation | Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada; Department of Clinical Biochemistry, University Health Network, Toronto, Canada |
contact email | eleftherios.diamandis@sinaihealth.ca |
lab head | |
Ashley Di Meo |
contact affiliation | University of Toronto |
contact email | ashley.dimeo@mail.utoronto.ca |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/10/PXD020192 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020192
- Label: PRIDE project
- Name: Proteomic Profiling of the Human Tissue and Biological Fluid Proteome