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PXD020186-3

PXD020186 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe HLA-Ligand-Atlas. A resource of natural HLA ligands presented on benign tissues
DescriptionA use case of the benign HLA-Ligand-Atlas is the prioritization of tumor-associated targets for e.g. peptide vaccination. Based on three glioblastoma samples, we illustrated how many of these peptides are covered in the benign dataset. The experimental and computational workflow for the isolation and identification of the glioblastoma immunopeptidomes is the same, as for all samples included in the HLA Ligand Atlas. As the three glioblastoma samples are not included in the HLA Ligand Atlas dataset, they have been deposited under a separate submission.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:21:11.205.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD020186
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterAna Marcu
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-07-03 07:21:42ID requested
12021-04-16 03:04:18announced
22021-04-18 22:03:05announced2021-04-19: Updated publication reference for PubMed record(s): 33858848.
32024-10-22 05:21:15announced2024-10-22: Updated project metadata.
Publication List
10.1136/jitc-2020-002071;
Marcu A, Bichmann L, Kuchenbecker L, Kowalewski DJ, Freudenmann LK, Backert L, M, ü, hlenbruch L, Szolek A, L, ü, bke M, Wagner P, Engler T, Matovina S, Wang J, Hauri-Hohl M, Martin R, Kapolou K, Walz JS, Velz J, Moch H, Regli L, Silginer M, Weller M, L, ö, ffler MW, Erhard F, Schlosser A, Kohlbacher O, Stevanovi, ć S, Rammensee HG, Neidert MC, HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy. J Immunother Cancer, 9(4):(2021) [pubmed]
10.6019/PXD020186;
Keyword List
submitter keyword: Human, HLA, Glioblastoma, Immunopeptidomics
Contact List
Hans-Georg Rammensee
contact affiliationDepartment of Immunology, Interfaculty Institute for Cell Biology, Eberhard Karls University Tübingen
contact emailhgrhgr2017@gmx.de
lab head
Ana Marcu
contact affiliationUniversity of Tübingen, Interfaculty Institute for Cell Biology, Department of Immunology
contact emailanamarcu.pe@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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