PXD020089 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | IRG1 Inflammasome Proteomics Experiments |
Description | BMDMs of indicated phenotypes were stimulated with LPS for 24h and analyzed or restimulated with LPS for additional 3h and analyzed. In some experiments 1mM itaconate was added at 4h of LPS first stimulation. |
HostingRepository | PRIDE |
AnnounceDate | 2021-09-09 |
AnnouncementXML | Submission_2021-09-09_00:54:10.853.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Kate Lizotte |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-06-29 02:19:09 | ID requested | |
⏵ 1 | 2021-09-09 00:54:11 | announced | |
Publication List
Bambouskova M, Potuckova L, Paulenda T, Kerndl M, Mogilenko DA, Lizotte K, Swain A, Hayes S, Sheldon RD, Kim H, Kapadnis U, Ellis AE, Isaguirre C, Burdess S, Laha A, Amarasinghe GK, Chubukov V, Roddy TP, Diamond MS, Jones RG, Simons DM, Artyomov MN, Itaconate confers tolerance to late NLRP3 inflammasome activation. Cell Rep, 34(10):108756(2021) [pubmed] |
Keyword List
submitter keyword: IRG1, BMDM, LPS, LCMS, itaconylation, Proteomics |
Contact List
Sebastian Hayes |
contact affiliation | Proteomics, Cell Metabolism, Agios, Cambridge, MA, USA |
contact email | Sebastian.Hayes@Agios.com |
lab head | |
Kate Lizotte |
contact affiliation | Agios |
contact email | Kate.Lizotte@Agios.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD020089 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020089
- Label: PRIDE project
- Name: IRG1 Inflammasome Proteomics Experiments