PXD020081-1

PXD020081 is an original dataset announced via ProteomeXchange.

Title	Phosphorylation level of SIRT1 in proliferating and senescent IMR90 cells
Description	Mammalian SIRT1 is a central regulator of metabolism and aging. This project is to analyze global phosphorylation levels of mammalian SIRT1 in proliferating and senescence states using human lung fibroblast IMR90, in order to explore the post-translational regulation of SIRT1 protein upon cellular senescence and its potential roles in the regulatory mechanisms of SIRT1 homeostasis.
HostingRepository	PRIDE
AnnounceDate	2020-09-29
AnnouncementXML	Submission_2020-09-28_22:30:43.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Congcong Lu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2020-06-29 01:02:30	ID requested
⏵ 1	2020-09-28 22:30:43	announced
2	2024-10-22 05:12:51	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: SIRT1, Phosphorylation, Senescence, IMR90

Benjamin A. Garcia
contact affiliation	Department of Biochemistry and Biophysics Penn Epigenetics Institute University of Pennsylvania School of Medicine
contact email	bgarci@pennmedicine.upenn.edu
lab head
Congcong Lu
contact affiliation	University of Pennsylvania School of Medicine
contact email	congclu@pennmedicine.upenn.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/09/PXD020081

PRIDE project URI

• PRIDE
  1. PXD020081
     1. Label: PRIDE project
     2. Name: Phosphorylation level of SIRT1 in proliferating and senescent IMR90 cells