PXD020009-2

PXD020009 is an original dataset announced via ProteomeXchange.

Title	The previously uncharacterized HCMV protein pUL13 increases mitochondrial bioenergetics during infection
Description	HCMV is a prevalent human pathogen which has been shown to globally alter cellular metabolism during its replication cycle, increasing central carbon metabolism, lipid metabolism, and OXPHOS. Here we demonstrate that the previously uncharacterized viral protein pUL13 is required for productive viral replication and sufficient to increase OXPHOS during infection.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:24:02.247.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Cora Betsinger
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-06-25 01:54:54	ID requested
1	2021-07-18 23:39:11	announced
⏵ 2	2024-10-22 05:24:02	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: pUL13,HCMV, OXPHOS, human, mitochondria, ETC

Ileana Cristea
contact affiliation	Princeton University
contact email	icristea@princeton.edu
lab head
Cora Betsinger
contact affiliation	Princeton University
contact email	corab@princeton.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/07/PXD020009

PRIDE project URI

• PRIDE
  1. PXD020009
     1. Label: PRIDE project
     2. Name: The previously uncharacterized HCMV protein pUL13 increases mitochondrial bioenergetics during infection