PXD019858 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Validation of itaconate modification on model proteins |
Description | This dataset was generated to confirm that +130 and +146 Da adducts observed in LPS-stimulated macrophages were produced by the itaconate metabolite. To this end, model proteins (bovine serum albumin and human KEAP1) were reacted in vitro with itaconate, and the correspondent adducts were analyzed by LC-MSMS |
HostingRepository | PRIDE |
AnnounceDate | 2021-07-22 |
AnnouncementXML | Submission_2021-07-22_11:30:50.399.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Alex Kentsis |
SpeciesList | scientific name: Bos taurus (Bovine); NCBI TaxID: 9913; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-06-17 22:24:05 | ID requested | |
⏵ 1 | 2021-07-22 11:30:50 | announced | |
2 | 2023-11-14 08:51:07 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
submitter keyword: itaconate chemoproteomics mass spectrometry SAMPEI adduct cysteine |
Contact List
Alex Kentsis |
contact affiliation | Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, 10021, USA. |
contact email | kentsisresearchgroup@gmail.com |
lab head | |
Alex Kentsis |
contact affiliation | Memorial Sloan Kettering Cancer Center |
contact email | kentsisresearchgroup@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD019858
- Label: PRIDE project
- Name: Validation of itaconate modification on model proteins