PXD019818-1

PXD019818 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Regulatory phosphorylation of eIF6 by GSK3
Description	The overall goal of this project is to determine the key sites in the C-terminus of eIF6 that are recognized and phosphorylated by GSK3. Analysis of kinase reactions using the site-specific mutants as well as the C-terminus deletion mutants of eIF6 indicated that there are GSK3-specific motifs in the C-terminus that are phosphorylated by GSK3. The purpose of the Mass Spectrometry studies is to use MS as a targeted and secondary approach to validate and identify GSK3-specific sites of phosphorylation in the C-terminus of eIF6.
HostingRepository	MassIVE
AnnounceDate	2020-07-23
AnnouncementXML	Submission_2020-07-23_12:28:38.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Greg Sabat
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Phospho
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-06-16 12:41:02	ID requested
⏵ 1	2020-07-23 12:28:39	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Phosphorylation, eIF6, kinase assay GSK3, priming, immunoprecipitation

submitter keyword: Phosphorylation, eIF6, kinase assay GSK3, priming, immunoprecipitation

Contact List

Dr. Sofia Origanti
contact affiliation	Saint Louis University
contact email	sofia.origanti@slu.edu
lab head
Greg Sabat
contact affiliation	University of Wisconsin
contact email	gsabat@wisc.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000085596/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000085596/