PXD019289 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative Proteomics comparison of total expressed proteomes of Anisakis simplex sensu stricto, A. pegreffii and their hybrid genotype |
Description | The total proteomes of Anisakis simplex s.s., A. pegreffii and their hybrid genotype have been compared by quantitative proteomics (iTRAQ approach), which considers the level of expressed proteins. A total of 1,976 proteins have been identified using public databases. One hundred ninety six proteins were found significantly differentially expressed; results of pairwise Log2 ratio comparisons among them were statistically treated and supported in order to convert them into discrete character states. This comparison selected thirty six proteins as discriminant biomarkers among A. simplex, A. pegreffii and their hybrid genotype; eighteen of these biomarkers, encoded by nine loci, are specific allergens of Anisakis (Ani s7, Ani s8, Ani s12 and Ani s14) and other (Ancylostoma secreted) is a common nematodes venom allergen. |
HostingRepository | PRIDE |
AnnounceDate | 2020-08-17 |
AnnouncementXML | Submission_2020-08-16_22:54:35.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD019289 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Sergio Ciordia |
SpeciesList | scientific name: Anisakis simplex complex; NCBI TaxID: 644710; |
ModificationList | iTRAQ4plex; Methylthio; Glu->pyro-Glu; Oxidation; Acetyl; Gln->pyro-Glu |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-05-19 01:06:44 | ID requested | |
⏵ 1 | 2020-08-16 22:54:36 | announced | |
Publication List
C Arcos S, Robertson L, Ciordia S, S, á, nchez-Alonso I, Careche M, Carballeda-Sanguiao N, Gonzalez-Mu, ñ, oz M, Navas A, , and Their Hybrid Genotype. Genes (Basel), 11(8):(2020) [pubmed] |
Keyword List
submitter keyword: Anisakis simplex, allergens, oesphageal glands, proteomics, excretion, secretion |
Contact List
Alfonso Navas |
contact affiliation | Museo Nacional de Ciencias Naturales. Dpto Biodiversidad y Biologia Evolutiva (CSIC) |
contact email | anavas@mncn.csic.es |
lab head | |
Sergio Ciordia |
contact affiliation | Spanish National Center for Biotechnology |
contact email | sciordia@cnb.csic.es |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD019289
- Label: PRIDE project
- Name: Quantitative Proteomics comparison of total expressed proteomes of Anisakis simplex sensu stricto, A. pegreffii and their hybrid genotype