PXD019249 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Quantitative proteomic analysis of mouse cerebellar granule cells after knockdown of YTHDF1 |
Description | To identify the target mRNAs of YTHDF1 in granule cells, we performed quantitative proteomic analysis. Mouse cerebellar granule cells were cultured and infected with lentiviral shYthdf1 or shCtrl. Proteins were extracted. After further processing, TMT-labeled peptides were subjected to LC-MS/MS analysis. We discovered 352 proteins that were differentially expressed altogether (change fold >1.2), among which 142 proteins were downregulated after YTHDF1 KD. This study provides a protein list which shows differentially expressed proteins after knockdown of YTHDF1 in granule cells. |
HostingRepository | PRIDE |
AnnounceDate | 2022-02-15 |
AnnouncementXML | Submission_2022-02-15_11:43:53.103.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jun Yu |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-05-18 01:03:09 | ID requested | |
⏵ 1 | 2022-02-15 11:43:54 | announced | |
Publication List
Yu J, She Y, Yang L, Zhuang M, Han P, Liu J, Lin X, Wang N, Chen M, Jiang C, Zhang Y, Yuan Y, Ji SJ, A Readers YTHDF1 and YTHDF2 Synergistically Control Cerebellar Parallel Fiber Growth by Regulating Local Translation of the Key Wnt5a Signaling Components in Axons. Adv Sci (Weinh), 8(22):e2101329(2021) [pubmed] |
Keyword List
submitter keyword: YTHDF1 |
YTHDF2 |
Local translation |
Contact List
ShengJian Ji |
contact affiliation | Department of Biology, Brain Research Center, Southern University of Science and Technology |
contact email | jisj@SUSTech.edu.cn |
lab head | |
Jun Yu |
contact affiliation | Southern University of Science and Technology |
contact email | 11650001@mail.sustech.edu.cn |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD019249 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD019249
- Label: PRIDE project
- Name: Quantitative proteomic analysis of mouse cerebellar granule cells after knockdown of YTHDF1