PXD019082 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | A2M Q975C and C3 Q1013C disulfide mutants |
Description | Mutant A2M and C3 with disulfides replacing their thiol esters were disulfide mapped via pepsin digests. |
HostingRepository | PRIDE |
AnnounceDate | 2021-02-18 |
AnnouncementXML | Submission_2021-02-18_00:36:26.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Seandean Harwood |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Eclipse |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-05-11 07:50:51 | ID requested | |
1 | 2021-02-18 00:15:09 | announced | |
⏵ 2 | 2021-02-18 00:36:27 | announced | 2021-02-18: Updated project metadata. |
Publication List
10.1021/ACS.BIOCHEM.0C00803; |
Harwood SL, Nielsen NS, Pedersen H, Kj, ΓΈ, ge K, Nielsen PK, Andersen GR, Enghild JJ, Substituting the Thiol Ester of Human A2M or C3 with a Disulfide Produces Native Proteins with Altered Proteolysis-Induced Conformational Changes. Biochemistry, 59(51):4799-4809(2020) [pubmed] |
Keyword List
submitter keyword: Human C3 A2M |
Contact List
Jan J. Enghild |
contact affiliation | MBG, Aarhus University, Denmark |
contact email | jje@mbg.au.dk |
lab head | |
Seandean Harwood |
contact affiliation | Aarhus University |
contact email | seandeanlykkeharwood@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD019082 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD019082
- Label: PRIDE project
- Name: A2M Q975C and C3 Q1013C disulfide mutants