PXD019044-1

PXD019044 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Effects of Canavanine on Human Glioblastoma Cells under Arginine Deprivation
Description	We investigated the effect of canavanine (toxic Arg analogue) treatment on U251MG and U87MG cell lines using a variety of methods including proteomics. Since 3rd isotope of unmodified peptide cannot be resolved from canavanine containing peptide even at extremely high resolutions of 480K we incorporated R13C615N4 into peptides to avoid MS1 overlap of Arg signals.
HostingRepository	PRIDE
AnnounceDate	2024-10-07
AnnouncementXML	Submission_2024-10-07_13:33:59.294.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Pavel Shliaha
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	6x(13)C; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-05-07 22:29:23	ID requested
⏵ 1	2024-10-07 13:34:00	announced

Publication List

Karatsai O, Shliaha P, Jensen ON, Stasyk O, R, ę, dowicz MJ, Combinatory Treatment of Canavanine and Arginine Deprivation Efficiently Targets Human Glioblastoma Cells via Pleiotropic Mechanisms. Cells, 9(10):(2020) [pubmed]
10.3390/cells9102217;

Karatsai O, Shliaha P, Jensen ON, Stasyk O, R, ę, dowicz MJ, Combinatory Treatment of Canavanine and Arginine Deprivation Efficiently Targets Human Glioblastoma Cells via Pleiotropic Mechanisms. Cells, 9(10):(2020) [pubmed]

10.3390/cells9102217;

Keyword List

submitter keyword: canavanine, SILAC,human

submitter keyword: canavanine, SILAC,human

Contact List

Ole N Jensen
contact affiliation	Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, Campusvej 55, DK - 5230 Odense M, Denmark(lab head)
contact email	jenseno@bmb.sdu.dk
lab head
Pavel Shliaha
contact affiliation	Syddansk University
contact email	pavels@bmb.sdu.dk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/10/PXD019044
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/10/PXD019044

PRIDE project URI

Repository Record List

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